Anthrax

  • Anthrax of skin causes ‘malignant pustule’ of the skin during its pathological process
  • Anthrax is an example of an enzootic
  • M' Fadyean reaction shows capsule in Anthrax 
  • Humans are usually resistant to infection in anthrax 
  • Less than 100 spores can cause pulmonary infection in anthrax
  • Anthrax Caused by Gram positive bacilli
  • Anthrax have Soil reservoir
  • Cutaneous anthrax generally resolve spontaneously
  • Capsular polypeptide in anthrax aids virulence by inhibiting phagocytosis
  • Plasmid in anthrax is responsible for toxin production
  • Anthrax is Caused by insect bite, rubbing of skin
  • Pulmonary infection occurs by inhalation
  • Anthrax bacilli differs from anthracoid bacilli by being Non-motile
  • Inverted fir tree appearance is characteristic Bacillus anthrax
  • The whole area is congested and edematous in cutaneous anthrax
  • Central crustation with black eschar is seen in cutaneous anthrax
  • Satellite nodule around inguinal region is seen in cutaneous anthrax
  • Woolsorter's disease is Pneumonic form of anthrax
  • Medusa head colonies on nutrient agar is seen in Anthrax
  • Commonest form of anthrax is Cutaneous type
  • PLET medium is used in Anthrax
  • An abattoir worker presented with a malignant pustule on his hand that progressed to form an ulcer. Smear was taken from the ulcer and sent to laboratory for investigation. The diagnosis is Cutaneous anthrax
  • According to The Workmen's Compensation Act, 1923, Anthrax is considered an occupational disease
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