ARSENIC POISIONING

  • Chronic arsenic poisoning Surest sign of identification
  • Suppose a body is lying in a desert and the person had been suffering from chronic arsenic poisoning while alive most common finding will be Mummification
  • Tissues that will hold the maximum concentration of arsenic in a person suspected to have died from arsenic poisoning is Liver
  • West Bengal is MOST affected by arsenic pollution in India
  • Arsenic inhibits PDH, Lipoic acid & α-KG dehydrogenase
  • Marsh's test & Reinsch test are used for arsenic poisoning
  • Arsenic causes Rain drop pigmentation
  • Chronic arsenic poisoning causes Mixed sensory and motor neuropathy
  • In a patient with acute arsenic poisoning arsenic deposits in Liver, Bone marrow & skin
  • In chronic arsenic poisoning the samples that can be sent for laboratory examinations are Nail clippings, Hair samples & Bone biopsy
  • Arsenic is used in treatment of Acute promyelocytic leukemia
  • Ingestion of arsenic causes Non cirrhotic portal fibrosis
  • Hairs are preserved in arsenic poisoning
  • Arsenic poisoning mimics Cholera
  • Arsenic poisoning presents with abdominal pain, diarrhea, Mees line on nails and myelosuppression
  • Chronic arsenic poisoning causes Mixed sensory and motor neuropathy, Hyperkeratosis of skin & Anemia
  • 'Red velvety' stomach mucosa is seen in poisoning with Arsenic poisoning
  • Arsenic causes Raindrop pigmentation, Alopecia & Palmar hyperkeratosis
  • Fatty yellow liver is seen in poisoning with Arsenic
  • The poison that can be detected in hair/bones long after death is Arsenic
  • Asymmetrical peripheral sensory neuropathy is seen in arsenic poisoning
  • Emaciation, Conjunctivitis running nose & Sensory motor polyneuropathy are features of chronic arsenic poisoning
  • Fatal dose of arsenic in adults is 100 to 200 mg
  • Black foot disease is caused by arsenic poisoning
  • Mee's line on nail is diagnostic of arsenic poisoning
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