Biotin And It's Deficiency

  • Biotin must be utilized during the conversion of acetyl CoA to malonyl CoA
  • The synthesis of glucose from pyruvate by gluconeogenesis Requires the participation of biotin
  • Acetyl CoA carboxylase requires Biotin for function
  • The activity of Carboxylase enzyme is affected by biotin deficiency
  • Rett's syndrome occurs due to deficiency of Biotin
  • Treatment of multiple carboxylase deficiency is biotin
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