EWING SARCOMA

  • CD-99 is marker of Ewing sarcoma
  • Fever is associated with poor prognosis in Ewings sarcoma
  • Genetic studies of a patient is positive for products of mic-2 gene is suggestive of Ewing’s sarcoma
  • The bone tumor seen in children with characteristic lamellated periosteal reaction with a mottled appearance and extension into soft tissue is Ewing’s sarcoma
  • S-100 is immunohistochemical markers would be expected to be positive in biopsies of Ewings Sarcoma
  • t(11;22) is associated with Ewing's sarcoma
  • Radiotherapy is the treatment of choice in Ewing's sarcoma
  • A patient with Ewing's sarcoma. Histology shows small round cells. These cells are filled with Glycogen
  • Ewings sarcoma arises from Neuroectodermal cells
  • Radiological finding of ewings sarcoma is Onion peel appearence
  • Chemotherapy of Ewings sarcoma includes Doxorubicin, Dactinomycin & Topotecan
  • Ewings sarcoma clinically mimics Osteomyelitis
  • Gene affected in Ewings sarcoma is EWS-FLI 1
  • Most common site of Ewing's sarcoma Shaft of femur
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