Hypothalamus

  • Prolactin secretion is tonically inhibited by the hypothalamus.
  • A lateral hypothalamic neuropeptide called hypocretin (orexin) is implicated in narcolepsy.
  • Function coordinated at the level of hypothalamus : Food intake , Hypophyseal control ,Temperature regulation.
  • Corticotropin releasing factor (CRF) released from the hypothalamic paraventricular nucleus is responsible for release of ACTH from pituitary.
  • In the CNS, the key regulators of sleep are located in Hypothalamus.
  • Preoptic nucleus of Hypothalamus is most closely related to sexual activity in males.
  • Injection of hypertonic saline in preoptic region of hypothalamus produces intense thirst.
  • Osmoreceptors are present in Anterior Hypothalamus.
  • Clomiphene Citrate induces gonadotropin secretion (LH, FSH) by blocking estrogenic feedback inhibition on hypothalamus.
  • Oxytocin is synthesized in Hypothalamus..
  • Shivering,Regulation of response to smell is controlled by Posterior Hypothalamus.
  • Thermoregulation in both ectotherms and endotherms is controlled mainly by the preoptic area of the anterior hypothalamus.
  • Reward Centre is located in Hypothalamus.
  • Satiety centre is located at Ventromedial nucleus of hypothalamus.
  • Endogenous pyrogens act by Raising thermostat point of hypothalamus.
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