NEURAL TUBE DEFECTS

  • Pre-conceptional intake of Folate results in decrease in incidence of neural tube defect
  • Myelomeningocele, Anencephaly & Encephalocele are neural tube defect
  • ↑Acetylcholinesterase is a marker for neural tube defects
  • Acetylcholinesterase is the Most useful maternal serum test used for distinguishing open neural tube defects and ventral wall defect in a fetus
  • Sodium valproate causes open neural tube defect
  • Neural tube defects are Multifactorial
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