PERTUSIS

  • Acellular pertusis vaccine contains Flagillary hemagglutinin, pertusis toxin, fimbriae
  • Pertusis toxin acts by Increase cyclic AMP, ADP ribosylation of proteins associated with receptors & Acts through G alpha subunit
  • Pertusis affects <5 br="" years=""> Carrier stage seen in Pertusis
  • The usual incubation period of pertusis is 7-14 days
  • Cross immunity is not seen with B. parapertusis
  • Chronic carrier state is not seen pertusis 
  • Secondary attack rate is 90% in pertusis 
  • Culture media for pertusis is Bordet gengou medium
Don't Forget to Solve all the previous Year Question asked on PERTUSIS