Prolactin

  • Prolactin secretion is tonically inhibited by the hypothalamus
  • Prolactin secretion is increased by Increased FSH,Increased libido, Increased testosterone,Sleep, Pregnancy & stress
  • Prolactinoma in pregnancy is Most common pituitary tumor but rarely symptomatic
  • Increase in prolactin levels worse prognosis of Prolactinoma in pregnancy
  • Hyperprolactinemia is a side effect of Metoclopramide
  • Initiation of lactation is affected by Progesterone ,Prolactin & HPL
  • Investigation of choice in hyperprolactinemia is Prolactin estimation
  • Decreased estrogen is a function of prolactin during lactation
  • Prolactin Highest during pregnancy and fall during lactation
  • A 30 year old woman presents with secondary amenorrhoea and galactorrhoea for 3 years is diagnosed to have Prolactinoma
  • Prolactinoma, Haloperidol & Hypothyroidism can cause hypersecretion of prolactin
  • Secretion of Prolactin is affected by dopamine
  • Prolactin secretion is inhibited by Bromocripitine
  • Cabergoline is preferred for infertility treatment of a female with increased prolactin levels
  • The most likely hormone increased in a middle aged female with a mass in sella turcica is prolactin 
  • Prolactinoma is the most common type of pituitary adenoma
  • A 30-year-old male complains of loss of erection; he has low testosterone and high prolactin level in blood is diagnosed to have Pituitary adenoma
  • Prolactin secretion is stimulated by TRH
  • A male presents with gynaecomastia, galactorrhoea and hypogonadism. Likely diagnosis is prolactinoma,
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