PUBERTY

  • In Testicular Feminization syndrome Gonadectomy is indicated At puberty
  • Most common cause of Puberty Menorrhagic is Anovulation
  • Puberty menorrhagia is treated by Progesterone, estrogen & GnRH analogues
  • Dilatation and curettage with blood transfusion is the primary treatment of puberty menorrhagia in a 16 years old girl with 3 gm% Hb
  • Bony deformities, hyperpigmentation of the skin, precocious puberty is seen in McCune Albright's syndrome
  • Precocious puberty is seen with Granulosa cell tumour
  • 'Congenital' erosion may reappear at Puberty
  • Puberty menorrhagia is Associated with anovulatory bleeding
  • Routine screening for bleeding disorder is done for Puberty menorrhagia
  • Hematinics & Hormone therapy is the treatment of choice in Puberty menorrhagia
  • Orchidopexy for cryptorchidism is done at the age of Puberty
  • 2:1 is the ratio of length of cervix and body of the uterus before puberty 
  • According to Tanner stages of development, Thelarche is the first sign of puberty in females
  • A neurosurgeon saw a child with precocious puberty and uncontrollable laughing. He suggested the parent of child to get a MRI done to evaluate for the possibility of Hypothalamic Hamartoma
  • The first sign of puberty in girls is Breast budding
  • Familial male limited precocious puberty is also called Testotoxicosis
  • Familial male limited precocious puberty is an Autosomal dominant condition
  • Flutamide can be used for treatment of Familial male limited precocious puberty
  • 35 gms is the approximate weight of thymus gland at puberty
  • The difference in the age of onset of puberty amongst males may be explained by Increased Inhibin levels
  • Estrogen is mainly responsible for skeletal maturation of long bones during puberty
  • Gamma amino butyric acid (GABA) has an inhibitory control over the GnRH neurons before the onset of puberty
  • Thelarche-puberche-growth spurt-menarche is the correct order of events at puberty in a girl
  • True precocious puberty can occur in Craniopharyngioma
  • Hypothalamic hamartoma, Mc Cune Albright syndrome & Granulosa cell tumor of human ovary may be causes of precocious puberty in girls
  • Delayed puberty seen in Chronic disease, Hypothyroidism & Turner's syndrome
  • Most common cause of delayed puberty in males is Constitutional
  • The diagnosis of a patient presenting with familial Polyostosis, Precocious puberty and Pigmentation is Mc Cune Albright syndrome
  • Infantile nucleus of the crystalline lens refers to the nucleus developed from Birth to puberty
  • Hormones required during puberty are LSH, Testesterone & Leptin
  • In congenital adrenal hyperplasia precocious puberty in male is due to 21 alpha hydroxylase deficiency
  • , 11(3 hydroxylase deficiency
  • First sign of puberty in female Tanner stage II
  • Sign of puberty in boys is Enlargement of testes
  • Delayed puberty in female Menarche > 16 year
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