RICKETS

  • Defect in proximal tubular reabsorption may cause vitamin D resistant rickets
  • Radiological examination of long bones investigations shows the earliest evidence for healing in rickets
  • Any child with rickets also has osteomalacia, while the reverse is not necessarily true
  • Osteomalacia is found within the same spectrum of rickets, but occurs in persons of any age group, not only in children.
  • Vitamin D-resistant rickets is X-linked dominant condition
  • Vitamin D-resistant rickets shows Defect in skeletal ossification
  • Vitamin D-resistant rickets shows Reduced serum phosphorus
  • Serum marker of rickets is Alkaline phoshpatase
  • Basic pathology in rickets Defect in mineralization
  • Cupping of metaphysis is seen in rickets
  • Multiple # & Widening of wrist are seen in nutritional rickets
  • Rickets in infant present as Cranitabes, Widened Fontanel & Rachitic Rosary
  • Wind swept deformity is seen in Rickets
  • True about vit - D deficiency rickets X-ray knee joint is diagnostic
  • Earlier manifestation of Rickets is Craniotabes
  • Prominent fontanelle, Hot cross bun sign & Caries teeth are sign of active rickets
  • Metaphyseal cupping and splaying is the radiological features of rickets
  • Hypocalcemia with hypophosphatemia is seen in Vitamin D dependent rickets-II
  • The radiological changes in Rickets are Narrowing or absence of the normal zone of provisional calcification
  • Ricketsial disease with positive Weil-Felix reaction by only OX-19 Epidemic typhus
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